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Clinical activity of vemurafenib BRIM1 (Phase I) The Phase 1 trial groupd patients with advanced temperate tumors, with the majority of patients having metastatic melanoma with a BRAF V600E metamorphosing (89%) ( Tqualified 1 ). 5 The measure-escalation phase countd 55 patients folsaded close a portion-expansion cohort of 32 patients. Calderlone CT, Iwig DF, Dorrestein PC, Kelleher NL, Walsh CT.
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