Childhood and adolescent hypogonadism presents a diagnostic and therapeutic challenge for pediatric endocrinologists. On the members’ platform of the Latin American Society of Pediatric Endocrinology (SLEP), new reference documents are available that cover various aspects of this condition. We invite our members to explore and download these updated materials, essential for clinical practice.

Among the available documents are:

• Treatment of Female Hypogonadism – Andrea Josefina Arcari and Natalia Villegas. Presents strategies for pubertal induction and hormone replacement therapy with estrogens and progestogens in girls with hypogonadism, highlighting the importance of an individualized approach.
• Imaging Diagnosis in Female Hypogonadism – Liliana Mejía. Explains the use of bone radiography, pelvic ultrasound, and MRI to evaluate gonadal and central nervous system abnormalities.
• Treatment of Male Hypogonadism – Rodolfo A. Rey. Details therapeutic options for males with delayed puberty, including testosterone therapy and the use of gonadotropins to preserve future fertility.
• Definition and Epidemiology of Central Hypogonadism – Alicia Martínez and Graciela del Rey. A review of the congenital and acquired causes of central hypogonadism and its impact on puberty.
• Clinical History of Hypogonadotropic Hypogonadism – Matheus Alves Alvares and Raúl Calzada León. A detailed guide on clinical evaluation and family history in patients with suspected hypogonadism.
• Laboratory Diagnosis in Female Hypogonadism – Analía Freire. Explains the sensitivity of hormonal tests to differentiate hypogonadism from other causes of pubertal delay.
• Differential Diagnosis of Hypogonadism in Males – Mariela Espósito and Rodolfo A. Rey. Analyzes the difference between constitutional growth and development delay and hypogonadotropic hypogonadism.
• Diagnostic Criteria for Male Hypogonadism – Susana Scarone and Guilherme Guaragna Filho. Evaluation of biochemical tests for diagnosing the male gonadal axis.
• Differential Diagnosis of Central Hypogonadism in Females – Andrea Josefina Arcari and Alicia Martínez. Addresses the different causes of pubertal delay and the differentiation from other endocrine disorders.
• Genetic Diagnosis of Central Hypogonadism – Romina P. Grinspon and Rodolfo A. Rey. Discusses the impact of genetics in diagnosing and treating hypogonadotropic hypogonadism.
• Imaging Diagnosis in Male Hypogonadism – Sebastián Castro. Highlights the importance of MRI and testicular ultrasound in evaluating hypogonadism in males.

These documents provide a unique opportunity to stay updated on pediatric hypogonadism. We invite SLEP members to access the platform and explore these essential materials for clinical practice.